Atherosclerosis and systemic lupus erythematosus
نویسندگان
چکیده
Systemic autoimmune diseases, such systemic lupus erythematosus (SLE), show an increased morbidity and cardiovascular mortality a higher incidence of early accelerated atherosclerosis than the general population that cannot be explained only by presence classic risk factors arterial hypertension, mellitus diabetes, hypercholesterolemia, obesity or smoking, but it seems to depend on associated with disease. The imbalance between vascular damage repair plays critical role in initiation atherosclerotic lesion. This balance may broken chronic inflammation, oxidative stress, pharmacological treatments, altered molecules cells involved endothelium. Research is ongoing identify biomarkers can help clinicians predict which SLE patients are greatest for
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ژورنال
عنوان ژورنال: Anales de la Real Academia Nacional de Medicina
سال: 2023
ISSN: ['0034-0634', '2605-2512']
DOI: https://doi.org/10.32440/ar.2023.140.01.rev03